Sesquiterpenoid Compounds from The Stembark of Aglaia minahassae (Meliaceae)
نویسندگان
چکیده
منابع مشابه
Triterpenes and steroids from the leaves of Aglaia exima (Meliaceae).
A study on the leaves of Aglaia exima led to the isolation of one new and seven known compounds: six triterpenoids and two steroids. Their structures were elucidated and analyzed mainly by using spectroscopic methods; 1D and 2D NMR, mass spectrometry, UV spectrometry and X-ray. All the triterpenoids and steroids were measured in vitro for their cytotoxic activities against eight cancer cell lin...
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In the title compound {systematic name: (1R,2R,5R,7R,10R,11R,14S,15R)-14-[(2S)-2-hy-droxy-6-methyl-hept-5-en-2-yl]-2,6,6,10,11-penta-methyl-tetra-cyclo-[8.7.0.0(2,7).0(11,15)]hepta-decan-5-ol monohydrate}, C(30)H(52)O(2)·H(2)O, the three fused cyclo-hexane rings adopt chair conformations and the hy-droxy substituent of one of these occupies an axial position. The fused cyclo-pentane ring adopts...
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Eleven rocaglamide derivatives (cyclopentatetrahydrobenzofurans) and one structurally related aglain congener all isolated from different Aglaia species (Meliaceae) were tested for growth inhibiting properties using the human cancer cell lines MONO-MAC-6 and MEL-JUSO. Proliferation of both cell lines was efficiently inhibited in a dose and compound dependent manner. Applying MTT-Assay, the IC50...
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The leaves from Aglaia andamanica were determined for their anti-allergic and anti-inflammatory effects using RBL2H3 and RAW264.7 cells, respectively. Among the isolated compounds, 24-epi-piscidinol A (5) exhibited the highest antiallergic activity against -hexosaminidase release with an IC50 value of 19.8 M, followed by (-)-yangambin (3, IC50 = 33.8 M), pyramidaglain A (8, IC50 = 37.1 M), ...
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ژورنال
عنوان ژورنال: Molekul
سال: 2018
ISSN: 2503-0310,1907-9761
DOI: 10.20884/1.jm.2018.13.1.410